The natives are friendly, there's sandy beaches and the sun beats down often - but there is one peculiarity that sets it apart from the rest of the world.
At puberty one in 90 children born there make a natural transformation from girl to boy.
Referred to as the ‘guevedoces’ which literally translates as ‘penis at 12’ - these children are known in medical terms as 'pseudohermaphrodite' - and feature in a new BBC 2 series called Countdown to Life - the Extraordinary Making of You.
“I remember I used to wear a little red dress,” said Johnny who at 24 was once known as Felecitia and did not have a penis.
“I was born at home instead of in a hospital. "They didn’t know what sex I was.
“I went to school and I used to wear my skirt. I never liked to dress as a girl.
"When they bought me girls toys I never bothered playing with them. All I wanted to do was play with the boys.”The guevedoces were uncovered by Cornell University endocrinologist Dr Julianne Imperato in the 1970s who travelled to the region to learn more about rumours that girls were morphing into boys.
And in the four decades since there have been studies, more has been learned about the perfectly natural condition.
Believed to have transpired through a rare genetic disorder, the condition is caused by a missing enzyme that prevents the production the male sex hormone - dihydro-testosterone - in the womb - and creates what looks like a baby girl on birth.
It is not until puberty, when testosterone flows, their voices break and they grow a male sexual reproductive organ that they become recognised as male.
BBC presenter Dr Michael Mosley said:
“I hated going through puberty; voice cracking, swinging moods, older brother laughing at me. But compared to Johnny, I had it easy.
“Guevedoces are also sometimes called “machihembras” meaning “first a woman, then a man.” "When they’re born they look like girls with no testes and what appears to be a vagina.
"It is only when they near puberty that the penis grows and testicles descend.
“When Dr Imperato investigated the Guavadoces she discovered the reason they don’t have male genitalia at birth is because they are deficient in an enzyme called 5-α-reductase, which normally converts testosterone into dihydro-testosterone.
“By a quirk of chance Dr Imperato’s research was picked up by the American pharmaceutical giant, Merck.
"They used her discovery to create a drug called finasteride, which blocks the action of 5-α-reductase.
“It is now widely used to treat benign enlargement of the prostate and male pattern baldness. For which, I’m sure, many men are truly grateful.”
UK Mirror



huh?
ReplyDelete#iT will only get better
#iT must end in praise
This is one of a kind!
DeleteWhat
DeleteHmnmmmm, I can't imagine myself as a man.. ....
ReplyDeleteHmnmmmm, I can't imagine myself as a man.. ....
ReplyDeleteWow strange and educative story, BTW madam Linda u no dey sleep??? Hope u get ur complete hrs of sleep ooo this one ur last to sleep and first to wake-up
ReplyDeleteWow. This is serious!
ReplyDeleteHmmm..ok o.
ReplyDeleteYou just can't hear it all, the strange things...
ReplyDeleteYour comment will be visible after approval.
Biochemistry
ReplyDelete~D great anonymous!
GUD FOR DEM....TOMJERRYSWIT
ReplyDeleteShit happens
ReplyDeleteLinda be teaching us a lot of tins we didnt knw dat existed........I'm glad to b a dedicated reader.nice piece
ReplyDeleteShe's not the one teaching you, you dummy, she's just sharing news from somewhere else.
DeleteHhehei! I was never going to believe this story till i read the line that it is "Believed to have transpired through a rare genetic
ReplyDeletedisorder, the condition is caused by a missing enzyme that
prevents the production the male sex hormone - dihydro-
testosterone - in the womb".
I guess that explains it all.
Now did somebody see the beauty of biochemistry? It goes down to the molecular level to explain the most complex things.
And I guess transgenders must be having the time of their lives stuffing synthetic analogues of a-reductase into their system to avoid production of male hormones.
Sincerely speaking the mind of Amadioha
Hhehei! I was never going to believe this story till i read the line that it is "Believed to have transpired through a rare genetic
ReplyDeletedisorder, the condition is caused by a missing enzyme that
prevents the production the male sex hormone - dihydro-
testosterone - in the womb".
I guess that explains it all.
Now did somebody see the beauty of biochemistry? It goes down to the molecular level to explain the most complex things.
And I guess transgenders must be having the time of their lives stuffing synthetic analogues of a-reductase into their system to avoid production of male hormones.
Sincerely speaking the mind of Amadioha
Na wah oo.....
ReplyDelete#abbytohxoft
Subhanallah!
ReplyDeletenawa o!
ReplyDeleteAunty linda.....
nawa o!
ReplyDeleteAunty linda.....
nawa o!
ReplyDeleteAunty linda.....
Hmmm
ReplyDeleteWow! Amazing! Hopefully they will be studied and not considered abnormal or cursed kids
ReplyDeleteThis is where they need to send onyx Godwin
ReplyDeleteNa wa o!
ReplyDeletePeople dey this world sha.
Hmmmmm
ReplyDeleteHmmm...wonders #singinavemaria
ReplyDeleteStrange...
ReplyDeleteHmmmmmm, mystery.
ReplyDeleteNna na wa o! Science is so confusing. Linda take note!
ReplyDeleteNna na wa o! Science is so confusing. Linda take note!
ReplyDeleteNna na wa o! Science is so confusing. Linda take note!
ReplyDeleteBorn trans
ReplyDeleteAnd you are a born moron
Deletea.k.a EDWIN CHINEDU AZUBUKO said...
ReplyDelete.
This is very shocking shah no doubt......
.
.
***CURRENTLY IN JUPITER***
Oh ok
ReplyDelete...this happens all over the world abeg
ReplyDeleteEeerie....life and its complexities
ReplyDeleteStrange
ReplyDeleteHmmm God is great. Mysteries and more to come which no man can explain. So if this exist what about the LGBT
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that is not really a big deal in medicine ..They are deficient of 5alpha reducatase an enzyme require to convert testosterone to Dihydrotestosterone which is needed for them to grow the external xteristic of a man ...But by puberty such hormones become sufficient and they are transformed ..As a matter of fact , humans are not classified male or female based on physical characteristic but due to the SRY GENES on the Y chromosomes ...Without these genes we will all be FEMALE by default .So the saying that Female are made from Male is a Wrong Saying, Rather Male are made from Female .(Tell your pastor next time you see him)
ReplyDeleteCopy cat!
DeleteMen possesses the Y n X chromosome while as women we Hv d X chromosome... what a man gives us women determines the offspring.... U r talking nonsense..
DeleteQuality Office Shirts and casual wears at affordable prices (Male and Female).
ReplyDeleteDelivery at your doorstep Nation wide.
BBM: 2754B912, Call: 08130373753
Whatsapp: 08034334692
Other items available:
Raulph Lauren Polos, Denim savage shirts, Jeans trousers,Chinoze, Pant Trousers, Round/ V neck, Jeans trousers
Tie- Complete set Curtis-Hawes and T.M Lewin
Italian Shoes etc.
It is well. Mo-1
ReplyDeleteWoow, dat was a nice one Linda, thanks for the information, Never heard this one b4.
ReplyDeletethis one get as e be
ReplyDeletewow, how possible?
ReplyDeleteThanks 4 d info
ReplyDeletewhy do we still have transgenders.
ReplyDeletewhy do we still have transgenders.
ReplyDeletena waah! God You Are Awesome indeed! http://www.bummyla.com
ReplyDeleteLike lizards?! WTF?!!
ReplyDeleteEhhh this one serious o....chai.....o ga ooo....very strange......n scary
ReplyDeleteSkin Paul, are you serious and for real then try write articles and educate some of us on stuffs like this so it will not come like news. Linda, please as much as you need money and fame, try and catch at least 7 hours of sleep to avoid any chaos for you,we all love you though, dont overcheat naturepls
ReplyDeleteCould it be something in water there? Probably some sloughs flowing downstream as remnants of industrial waste? That could have a teratogenic effect which may likely cause issues as this. Until I could rule out environmental factors, I will take this with a grain of salt.
ReplyDeleteThe Austinite... Love is God is Love
That's serious
ReplyDelete